epidemiology

Bayesian imputation of time-varying covariates in linear mixed models

Studies involving large observational datasets commonly face the challenge of dealing with multiple missing values. The most popular approach to overcome this challenge, multiple imputation using chained equations, however, has been shown to be …

Mothers’ intake of sugar-containing beverages during pregnancy and body composition of their children during childhood: the Generation R Study

**Background:** High intake of sugar-containing beverages (SCBs) has been linked to increased risk of obesity. However, associations of SCB intake during pregnancy with child body composition have been unclear. **Objectives:** We explored whether SCB …

Development of a Healthy Aging Score in the Population-Based Rotterdam Study: Evaluating Age and Sex Differences

**Objectives:** To develop a healthy aging score (HAS), to assess age and sex differences in HAS, and to evaluate the association of the HAS with survival. **Design:** Prospective population-based cohort. **Setting:** Inhabitants of Ommoord, …

Dealing with missing covariates in epidemiologic studies: A comparison between multiple imputation and a full Bayesian approach

Incomplete data are generally a challenge to the analysis of most large studies. The current gold standard to account for missing data is multiple imputation, and more specifically multiple imputation with chained equations (MICE). Numerous studies …